PD-1 cDNA Clone: Expression and Clone Vector / Plasmid
PD-1 cDNA / Gene Overview
PDCD1 gene / cDNA is a protein-coding gene which located on 2q37.3. The PDCD1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.168 organisms have orthologs with human gene PDCD1.
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
PD-1 cDNA / Gene Sequence
LOCUS NM_005018 2115 bp mRNA linear PRI 05-AUG-2018
Homo sapiens programmed cell death 1 (PDCD1), mRNA.
This sequence information is just for reference only.
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