LIF cDNA Clone: Expression and Clone Vector / Plasmid
LIF cDNA / Gene Overview
LIF gene / cDNA is a protein-coding gene which located on 22q12.2. The LIF gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.171 organisms have orthologs with human gene LIF.
More LIF reagents
LIF General Information
LIF cDNA / Gene Function
The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
LIF cDNA / Gene Sequence
LOCUS
LOCUS NM_002309 3987 bp mRNA linear PRI 25-JUN-2018
DEFINITION
Homo sapiens LIF, interleukin 6 family cytokine (LIF), transcript variant 1, mRNA.
ACCESSION
NM_002309
VERSION
NM_002309.4
This sequence information is just for reference only.
LIF Family & Reagents
Gene family
LIF Gene family reagents (Endogenous ligands)
LIF cDNA / Gene Alias
- CDF
- cholinergic differentiation factor
- DIA
- differentiation inhibitory activity
- differentiation-inducing factor
- hepatocyte-stimulating factor III
- HILDA
- human interleukin in DA cells
LIF cDNA / Gene Expression
Broad expression in gall bladder (RPKM 20.9), appendix (RPKM 11.6) and 16 other tissues
