IkB alpha cDNA Clone: Expression and Clone Vector / Plasmid
IkB alpha cDNA / Gene Overview
NFKBIA gene / cDNA is a protein-coding gene which located on 14q13.2. The NFKBIA gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, and frog.230 organisms have orthologs with human gene NFKBIA.
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
IkB alpha cDNA / Gene Sequence
LOCUS NM_020529 1579 bp mRNA linear PRI 22-JUL-2018
Homo sapiens NFKB inhibitor alpha (NFKBIA), mRNA.
This sequence information is just for reference only.
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