DDR1 cDNA Clone: Expression and Clone Vector / Plasmid

DDR1 cDNA / Gene Overview

DDR1 gene / cDNA is a protein-coding gene which located on 6p21.33. The DDR1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, and frog.165 organisms have orthologs with human gene DDR1.

DDR1 cDNA / Gene Function

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

DDR1 cDNA / Gene Sequence

LOCUS
LOCUS NM_013994 3678 bp mRNA linear PRI 29-JUL-2018
DEFINITION
Homo sapiens discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 3, mRNA.
ACCESSION
NM_013994
VERSION
NM_013994.2

This sequence information is just for reference only.

DDR1 Family & Reagents

DDR1 Gene family reagents (Receptor Tyrosine Kinases)

Approved Symbol Reagent list
IGF1R
MST1R
MERTK
RET
FGFR1
ROR2
KDR
KIT
FGFR2
FLT4
Approved Symbol Reagent list
CSF1R
MUSK
Tie1
PDGFRB
NTRK3
FGFR4
NTRK1
TEK
FLT1
MET

DDR1 Gene family reagents (CD molecules)

Approved Symbol Reagent list
TNFRSF4
IL13Ra1
MS4A1
CD59
CD244
BSG
TLR2
CEACAM1
CLEC12A
CD300E
Approved Symbol Reagent list
FCGR3B
LIFR
GYPA
JAG1
CEACAM3
TNFRSF8
CD82
LAIR1
ADAM8
CD47

DDR1 cDNA / Gene Alias

  • CD167
  • RTK6

DDR1 cDNA / Gene Expression

Ubiquitous expression in brain (RPKM 49.5), thyroid (RPKM 24.8) and 22 other tissues