CD28 cDNA Clone: Expression and Clone Vector / Plasmid

CD28 cDNA / Gene Overview

CD28 gene / cDNA is a protein-coding gene which located on 2q33.2. The CD28 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog.198 organisms have orthologs with human gene CD28.

CD28 cDNA / Gene Function

The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]

CD28 cDNA / Gene Sequence

LOCUS
LOCUS NM_006139 4900 bp mRNA linear PRI 15-JUL-2018
DEFINITION
Homo sapiens CD28 molecule (CD28), transcript variant 1, mRNA.
ACCESSION
NM_006139
VERSION
NM_006139.3

This sequence information is just for reference only.

CD28 Family & Reagents

CD28 Gene family reagents (CD molecules)

Approved Symbol Reagent list
TNFRSF4
CD7
CLEC10A
IGSF8
MSR1
CD69
ICOS
FAS
CD8B
SDC1
Approved Symbol Reagent list
CD2
CD6
SPN
SLAMF7
LAIR2
ENTPD1
ANPEP
GYPC
CD209
IL10RA

CD28 Gene family reagents (V-set domain containing)

Approved Symbol Reagent list
CD7
NCR2
PIGR
SIGLEC5
CD2
BTN3A3
TREM1
SIGLEC6
SCN2B
CD274
Approved Symbol Reagent list
PILRA
VSIG8
BTN3A1
CD80
CEACAM5
F11R
NECTIN1
MOG
CEACAM1
GPA33

CD28 Gene family reagents (Ig-like cell adhesion molecule family)

Approved Symbol Reagent list
ICAM1
ICAM4
MCAM
NECTIN2
CD96
JAM3
NCAM2
CNTN4
SLAMF1
SIRPG
Approved Symbol Reagent list
CADM1
CD58
CADM3
L1CAM
ROBO2
SLAMF6
CD47
JAML
UNC5B
VCAM1

CD28 cDNA / Gene Alias

  • T-cell-specific surface glycoprotein

CD28 cDNA / Gene Expression

Biased expression in lymph node (RPKM 11.2), appendix (RPKM 7.3) and 7 other tissues

Recombinant CD28 protein citations

Title
The role of Th1 / Th2 Cytokines played in Regulation of Specific CD4 + Th1 Cells Conversion and Activation during Inflammatory Reaction of Chronic Obstructive Pulmonary Disease
Year
2018
Author
Sun, J;Liu, T;Yan, Y;Huo, K;Zhang, W;Liu, H;Shi, Z;
Journal
Scand. J. Immunol.