Transferrin cDNA Clone: Expression and Clone Vector / Plasmid

Transferrin cDNA / Gene Overview

TF gene / cDNA is a protein-coding gene which located on 3q22.1. The TF gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, and frog.94 organisms have orthologs with human gene TF.

Transferrin cDNA / Gene Function

This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]

Transferrin cDNA / Gene Sequence

LOCUS
LOCUS NM_001063 2808 bp mRNA linear PRI 05-AUG-2018
DEFINITION
Homo sapiens transferrin (TF), transcript variant 1, mRNA.
ACCESSION
NM_001063 NM_014111
VERSION
NM_001063.3

This sequence information is just for reference only.

Transferrin Family & Reagents

Gene family

Transferrin Gene family reagents (Transferrins)

Approved Symbol Reagent list
LTF
Approved Symbol Reagent list
MELTF

Transferrin cDNA / Gene Alias

  • PRO1557
  • PRO2086
  • serotransferrin

Transferrin cDNA / Gene Expression

Restricted expression toward liver (RPKM 1622.3)

Recombinant Transferrin protein citations

Title
Iron-deficiency and estrogen are associated with ischemic stroke by up-regulating transferrin to induce hypercoagulability
Year
2019
Author
Tang, X;Fang, M;Cheng, R;Zhang, Z;Wang, Y;Shen, C;
Journal
bioRxiv
Title
Transferrin plays a central role to maintain coagulation balance by interacting with clotting factors
Year
2019
Author
Tang, X;Zhang, Z;Fang, M;Han, Y;Wang, S;Xue, M;Li, Y;
Journal
bioRxiv