PSG1 (Protein | Antibody | cDNA Clone | ELISA Kit)

All PSG1 reagents are produced in house and quality controlled, including 5 PSG1 Antibody, 13 PSG1 Gene, 2 PSG1 Lysate, 2 PSG1 Protein, 1 PSG1 qPCR. All PSG1 reagents are ready to use.

PSG1 Protein (2)

    PSG1 Antibody (5)

      PSG1 cDNA Clone (13)

      BC058285

      PSG1 qPCR Primer (1)

      PSG1 Lysate (2)

        PSG1 Background

        Pregnancy-specific glycoproteins (PSGs) are a family of Ig-like proteins secreted by specialized placental cells. The PSG1 structure is composed of a single Ig variable region-like N-terminal domain and three Ig constant region-like domains termed A1, A2, and B2. Members of the human and murine PSG family have been shown to induce anti-inflammatory cytokines from monocytes and macrophages and to stimulate angiogenesis.Two distinct domains of PSG1 are involved in the regulation of TGF-beta1 and provide a mechanistic framework for how PSGs modulate the immunoregulatory environment at the maternal-fetal interface for successful pregnancy outcome.

        Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.