N Cadherin cDNA Clone: Expression and Clone Vector / Plasmid
N Cadherin cDNA / Gene Overview
CDH2 gene / cDNA is a protein-coding gene which located on 18q12.1. The CDH2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.216 organisms have orthologs with human gene CDH2.
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]
N Cadherin cDNA / Gene Sequence
LOCUS NM_001792 4339 bp mRNA linear PRI 12-AUG-2018
Homo sapiens cadherin 2 (CDH2), transcript variant 1, mRNA.
This sequence information is just for reference only.
N Cadherin Gene family reagents (Type I classical cadherins)
N Cadherin cDNA / Gene Alias
N Cadherin cDNA / Gene Expression
Biased expression in heart (RPKM 64.0), adrenal (RPKM 32.7) and 7 other tissues
Recombinant N Cadherin protein citations
Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance, impairment of insulin signaling and down-stream eNOS activation, in human aortic endothelial cells after short- or long-term exposure to TNFα
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