N Cadherin cDNA Clone: Expression and Clone Vector / Plasmid

N Cadherin cDNA / Gene Overview

CDH2 gene / cDNA is a protein-coding gene which located on 18q12.1. The CDH2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.216 organisms have orthologs with human gene CDH2.

N Cadherin cDNA / Gene Function

This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]

N Cadherin cDNA / Gene Sequence

LOCUS
LOCUS NM_001792 4339 bp mRNA linear PRI 12-AUG-2018
DEFINITION
Homo sapiens cadherin 2 (CDH2), transcript variant 1, mRNA.
ACCESSION
NM_001792
VERSION
NM_001792.4

This sequence information is just for reference only.

N Cadherin Family & Reagents

N Cadherin Gene family reagents (CD molecules)

Approved Symbol Reagent list
MPL
CD82
GGT1
LAMP3
TNFRSF10C
LAG3
SIGLEC6
FCGR3B
IL1R1
PVR
Approved Symbol Reagent list
IL2RA
ENPEP
EpCAM
PDGFRB
KIT
TNFSF4
CD22
ADGRE5
SEMA4D
CSF1R

N Cadherin Gene family reagents (Type I classical cadherins)

Approved Symbol Reagent list
CDH1
CDH4
Approved Symbol Reagent list
CDH15
   

N Cadherin cDNA / Gene Alias

  • CD325
  • CDHN
  • N-cadherin

N Cadherin cDNA / Gene Expression

Biased expression in heart (RPKM 64.0), adrenal (RPKM 32.7) and 7 other tissues

Recombinant N Cadherin protein citations

Title
Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance, impairment of insulin signaling and down-stream eNOS activation, in human aortic endothelial cells after short- or long-term exposure to TNFα
Year
2018
Author
Sasaki, N;Itakura, Y;Toyoda, M;
Journal
Oncotarget