ICOS cDNA Clone: Expression and Clone Vector / Plasmid

ICOS cDNA / Gene Overview

ICOS gene / cDNA is a protein-coding gene which located on 2q33.2. The ICOS gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.130 organisms have orthologs with human gene ICOS.

More ICOS reagents

ICOS cDNA / Gene Function

The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]

ICOS cDNA / Gene Sequence

LOCUS
LOCUS NM_012092 2652 bp mRNA linear PRI 22-JUL-2018
DEFINITION
Homo sapiens inducible T cell costimulator (ICOS), mRNA.
ACCESSION
NM_012092
VERSION
NM_012092.3

This sequence information is just for reference only.

ICOS Family & Reagents

Gene family

ICOS Gene family reagents (CD molecules)

Approved Symbol Reagent list
LAMP3
CD5
CD86
CSF2RA
CD302
BST2
TLR4
CD14
CLEC4M
ALCAM
Approved Symbol Reagent list
CDCP1
CTLA4
TNFRSF4
SELE
SDC2
IL5RA
SPN
IGF1R
IL12RB1
KLRK1

ICOS cDNA / Gene Alias

  • activation-inducible lymphocyte immunomediatory molecule
  • AILIM
  • CD278

ICOS cDNA / Gene Expression

Biased expression in lymph node (RPKM 7.8), bone marrow (RPKM 6.5) and 9 other tissues