Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity).
HMMR/RHAMM protein expression
Expressed in breast cancer cell lines and in normal breast tissue.
HMMR cDNA / gene is a gene with protein product which located on 5q34. The HMMR gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 216 organisms have orthologs with human gene HMMR.
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