GITR cDNA Clone: Expression and Clone Vector / Plasmid
GITR cDNA / Gene Overview
TNFRSF18 gene / cDNA is a protein-coding gene which located on 1p36.33. The TNFRSF18 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.178 organisms have orthologs with human gene TNFRSF18.
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
GITR cDNA / Gene Sequence
LOCUS NM_004195 1214 bp mRNA linear PRI 23-JUN-2018
Homo sapiens TNF receptor superfamily member 18 (TNFRSF18), transcript variant 1, mRNA.
This sequence information is just for reference only.
Successfully added to cart Please enter catalog numberSubmitted successfullyNetwork ErrorPlease enter your company namePlease enter your namePlease enter your emailPlease enter a valid email addressPlease enter some message