SSEA1 / FUT4: SSEA1 / FUT4 Protein | SSEA1 / FUT4 Antibody

SSEA1 / FUT4 Gene family

SSEA1 / FUT4 Background

Fucosyltransferase IV (FUT4) is the key enzyme for the biosynthesis of alpha1,3-fucosylated glycans carried by glycoproteins, and the previous studies showed FUT4 expression changed dynamically during perimplantation. miR-2c and FUT4 may be applied together as the potential markers for endometrial receptivity, and useful diagnostic and therapeutic targets for infertility. Increased expression of fucosyltransferase4 (FUT4) has been reported to be associated with the invasive and metastatic properties of colorectal cancer (CRC). Fucosyltransferase IV (FUT4) is associated with the proliferation and metastasis of breast cancer, FUT4 can serve as novel biomarker in the diagnosis and prognosis of breast cancer. FUT4 is an essential enzyme that catalyzes the synthesis of Lewis Y (LeY) oligosaccharides.

Reference for SSEA1 / FUT4

  • Zheng Q, et al. (2017) Microrna-200c impairs uterine receptivity formation by targeting fut4 and alpha1,3-fucosylation. Cell Death Differ 24(12), 2161-2172.
  • Li Y, et al. (2017) Tumor-suppressive mir-26a and mir-26b inhibit cell aggressiveness by regulating fut4 in colorectal cancer. Cell Death Dis 8(6), e2892.
  • Yan X, et al. (2015) Fucosyltransferase iv (fut4) as an effective biomarker for the diagnosis of breast cancer. Biomed Pharmacother 70(299-304.
  • Yang X, et al. (2014) Hsf1 and sp1 regulate fut4 gene expression and cell proliferation in breast cancer cells. J Cell Biochem 115(1), 168-178.

SSEA1 / FUT4 Protein

SSEA1 / FUT4 protein function

May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.

SSEA1 / FUT4 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (Da)

SSEA1 / FUT4 Antibody

There are 3 SSEA1 / FUT4 antibodies which are validated in multiple tissues with various applications, including IHC-P, WB. There are 2 SSEA1 / FUT4 antibody for IHC-P, 1 SSEA1 / FUT4 antibody for WB. Among all these SSEA1 / FUT4 antibodies, there are 3 anti-SSEA1 / FUT4 rabbit polyclonal antibodies . All the SSEA1 / FUT4 anbodies are produced in house and all are in stock. SSEA1 / FUT4 antibody customerized service is available.

SSEA1 / FUT4 Gene

FUT4 gene / cDNA is a protein-coding gene which located on 11q21. The FUT4 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog.172 organisms have orthologs with human gene FUT4.