CD89 Protein

CD89 Protein Overview

CD89 reagents

Human Fc-alpha receptor (FCAR) is present on a number of cell types, including neutrophils, monocytes, macrophages, and eosinophils. FCAR interacts with aggregated IgAs, such as IgA coated on the surface of an invading microorganism, and mediates several immunologic defense processes such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. FCAR is a glycoprotein of 50 to 100 kD, with diversity on different cell types (summary by Maliszewski et al., 1990).

CD89 protein name

Recommended name
Immunoglobulin alpha Fc receptor
Short name
IgA Fc receptor
Aliases
CD89
Alternative name
CD_antigen: CD89

CD89 Gene family protein

CD89 Protein Sequence

Species Human CD89 protein
Length 287
Mass (Da) 32265
Sequence Human CD89 protein sequence
Species
Length
Mass (Da)
Sequence
Species
Length
Mass (Da)
Sequence

CD89 Protein Molecular Weight & PI

Immunoglobulin alpha Fc receptor precursor (IgA Fc receptor) (CD89 antigen) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 22-287 Immunoglobulin alpha Fc receptor.

Molecular weight (Da)

29938.12

Theoretical pI

6.25

CD89 Protein Structure

Crystal structure of human FcaRI
Deposited
2003-03-27   Released:  2003-05-27
Deposition Author(s)
Herr, A.B., Ballister, E.R., Bjorkman, P.J.
Organism(s)
Homo sapiens
Expression System
Trichoplusia ni
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
3.0000 Å
R-Value Free
0.292
R-Value Work
0.235
1OVZ From PDB

Human CD89 protein Secondary structure

CD89 Protein Interaction

Recombinant CD89 Protein Feature

CD89 Protein, Rat, Recombinant (His Tag)

High Purity
> 95 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method

Bulk Order of Recombinant CD89 Protein

Please Leave Us a Message if you have any questions regarding bulk price quote of our products on the website, our customer specialist will get back to you in 24 hours by email.

Custom Recombinant Protein Production Service Features

  • Over 10 years' experience for 6000+ recombinant proteins production.
  • One-stop service from gene synthesis and vector construction to protein expression and purification.
  • Multiple protein expression systems: bacterial, yeast, baculovirus-insect and mammalian expression system.
  • Multiple purification systems (30+) to choose.
  • High R & D ability with over 1000 new proteins per year and quick problem-solving ability.
  • Close to 100 bioreactors with various volume between 2-1000 L to guarantee high-throughput and large-scale production.

Custom Recombinant Protein Production Service Advantages

  • High-efficiency expression vectors
  • High cell density culturing
  • Proprietary medium formulation
  • >6000 proteins expression and purification experience
  • High-efficiency expression vectors
  • High cell density culturing

Recombinant Protein Production Service Description

We offer one-stop services for recombinant protein production using our advanced protein expression platform technologies. Our full services include protein gene synthesis, protein codon optimization, protein expression vector design, large scale cell culture and fermentation, protein purification, and protein quality control testing. We offer significant cost saving advantages and record speed in protein expression and bulk production. We also have extensive experiences and expertise in handling various types of recombinant protein purification projects, with or without purification tags.