CD16 / FCGR3 Protein

CD16 / FCGR3 Protein Overview

CD16 / FCGR3 reagents

NEUTROPHIL-SPECIFIC ANTIGEN NA1, INCLUDEDNEUTROPHIL-SPECIFIC ANTIGEN NA2, INCLUDEDNEUTROPHIL-SPECIFIC ANTIGEN NC1, INCLUDED

CD16 / FCGR3 protein name

Short name
IgG Fc receptor III||FcRIII
Alternative name
Fc-gamma RIII CD_antigen: CD16

CD16 / FCGR3 Protein Sequence

Species
Length
Mass (Da)
Sequence
Species Mouse CD16 / FCGR3 protein
Length 267
Mass (Da) 30282
Sequence Mouse CD16 / FCGR3 protein sequence
Species Rat CD16 / FCGR3 protein
Length 257
Mass (Da) 29062
Sequence Rat CD16 / FCGR3 protein sequence

CD16 / FCGR3 Protein Molecular Weight & PI

Low affinity immunoglobulin gamma Fc region receptor III precursor (IgG Fc receptor III) (Fc-gamma RIII) (FcRIII) (CD16 antigen) Mus musculus (Mouse).

CD16 / FCGR3 Protein Interaction

Recombinant CD16 / FCGR3 Protein Feature

CD16 / FCGR3 Protein, Rhesus, Recombinant (His Tag)

High Purity
> 95 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
High Activity
Measured by its binding ability in a functional ELISA. Immobilized Rhesus FCGR3-His (cat:90013-C08H) at 10 μg/ml (100 μl/well) can bind recombinant human IgG1 (Fc) (Cat:10702-HNAC). The EC50 of human IgG1 (Fc) (Cat:10702-HNAC) is 0.35-0.81 μg/ml.

Recombinant CD16 / FCGR3 protein citations

Title
Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant
Year
2011
Author
Zeitlin, L;Pettitt, J;Scully, C;Bohorova, N;Kim, D;Pauly, M;Hiatt, A;Ngo, L;Steinkellner, H;Whaley, KJ;Olinger, GG;
Journal
Proc. Natl. Acad. Sci. U.S.A.
Title
Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples ☆
Year
2014
Author
Pierog, P;Krishna, M;Yamniuk, A;Chauhan, A;
Journal
Journal of Immunological Methods
Title
Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples
Year
2015
Author
Pierog, P;Krishna, M;Yamniuk, A;Chauhan, A;DeSilva, B;
Journal
J. Immunol. Methods
Title
Conserved FcγR- glycan discriminates between fucosylated and afucosylated IgG in humans and mice.
Year
2017
Author
Dekkers, G;Bentlage, AEH;Plomp, R;Visser, R;Koeleman, CAM;Beentjes, A;Mok, JY;van Esch, WJE;Wuhrer, M;Rispens, T;Vidarsson, G;
Journal
Mol. Immunol.

Bulk Order of Recombinant CD16 / FCGR3 Protein

Please Leave Us a Message if you have any questions regarding bulk price quote of our products on the website, our customer specialist will get back to you in 24 hours by email.

Custom Recombinant Protein Production Service Features

  • Over 10 years' experience for 6000+ recombinant proteins production.
  • One-stop service from gene synthesis and vector construction to protein expression and purification.
  • Multiple protein expression systems: bacterial, yeast, baculovirus-insect and mammalian expression system.
  • Multiple purification systems (30+) to choose.
  • High R & D ability with over 1000 new proteins per year and quick problem-solving ability.
  • Close to 100 bioreactors with various volume between 2-1000 L to guarantee high-throughput and large-scale production.

Custom Recombinant Protein Production Service Advantages

  • High-efficiency expression vectors
  • High cell density culturing
  • Proprietary medium formulation
  • >6000 proteins expression and purification experience
  • High-efficiency expression vectors
  • High cell density culturing

Recombinant Protein Production Service Description

We offer one-stop services for recombinant protein production using our advanced protein expression platform technologies. Our full services include protein gene synthesis, protein codon optimization, protein expression vector design, large scale cell culture and fermentation, protein purification, and protein quality control testing. We offer significant cost saving advantages and record speed in protein expression and bulk production. We also have extensive experiences and expertise in handling various types of recombinant protein purification projects, with or without purification tags.