The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
CD155 / PVR cDNA / Gene Sequence
LOCUS NM_006505 5903 bp mRNA linear PRI 23-JUL-2018
Homo sapiens poliovirus receptor (PVR), transcript variant 1, mRNA.
This sequence information is just for reference only.
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