C1 inhibitor cDNA Clone: Expression and Clone Vector / Plasmid
C1 inhibitor cDNA / Gene Overview
SerpinG1 gene / cDNA is a protein-coding gene which located on 11q12.1. The SERPING1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and zebrafish.162 organisms have orthologs with human gene SERPING1.
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, Jul 2008]
C1 inhibitor cDNA / Gene Sequence
LOCUS NM_000062 1984 bp mRNA linear PRI 16-JUL-2018
Homo sapiens serpin family G member 1 (SERPING1), transcript variant 1, mRNA.
This sequence information is just for reference only.
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