BTN3A2 Protein

BTN3A2 Protein Overview

BTN3A2 reagents

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (601610) and the BTN2 (e.g., BTN2A1; 613590) and BTN3 (e.g., BNT3A2) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010).

BTN3A2 protein family

Belongs to the immunoglobulin superfamily. BTN/MOG family.

BTN3A2 protein name

Recommended name
Butyrophilin subfamily 3 member A2

BTN3A2 Protein Sequence

Species Human BTN3A2 protein
Length 334
Mass (Da) 36428
Sequence Human BTN3A2 protein sequence
Mass (Da)
Mass (Da)

BTN3A2 Protein Molecular Weight & PI

Butyrophilin subfamily 3 member A2 precursor Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 30-334 Butyrophilin subfamily 3 member A2.

Molecular weight (Da)


Theoretical pI


BTN3A2 Protein Structure

Crystal Structure of the Human BTN3A2 Ectodomain
2012-05-17   Released:  2012-08-08
Deposition Author(s)
Palakodeti, A., Sandstrom, A., Sundaresan, L., Harly, C., Nedellec, S., Olive, D., Scotet, E., Bonneville, M., Adams, E.J.
Homo sapiens
Expression System
Trichoplusia ni
Experimental Data Snapshot
2.3790 Å
R-Value Free
R-Value Work
4F8Q From PDB

Human BTN3A2 protein Secondary structure

BTN3A2 Protein Interaction

Recombinant BTN3A2 Protein Feature

BTN3A2 Protein, Human, Recombinant (His Tag)

High Purity
> 95 % as determined by SDS-PAGE.
Low Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.

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