BirA Protein

BirA Protein Overview

BirA reagents

Holocarboxylase synthetase (EC 6.3.4.10) covalently links biotin to propionyl-CoA carboxylase (PCCA; 232000), pyruvate carboxylase (PC; 608786), alpha-methylcrotonyl-CoA carboxylase (MCCC1; 609010), and acetyl-CoA carboxylase (ACACA; 200350).

BirA protein name

Alternative name
Biotin operon repressor Biotin--[acetyl-CoA-carboxylase] ligase Biotin--protein ligase Biotin-[acetyl-CoA carboxylase] synthetase

BirA Protein Molecular Weight & PI

Bifunctional ligase/repressor BirA (Biotin operon repressor) (Biotin--[acetyl-CoA-carboxylase] ligase) (EC 6.3.4.15) (Biotin--protein ligase) (Biotin-[acetyl-CoA carboxylase] synthetase) Escherichia coli (strain K12).

BirA Protein Structure

CRYSTAL STRUCTURE OF E. COLI BIOTIN REPRESSOR WITH BOUND BIOTIN
Deposited
2001-01-12   Released:  2001-05-30
Deposition Author(s)
Kwon, K., Streaker, E.D., Ruparelia, S., Beckett, D.
Organism(s)
Escherichia coli (strain K12)
Expression System
Escherichia coli
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.4000 Å
R-Value Work
0.189
1HXD From PDB

Human BirA protein Secondary structure

BirA Protein Interaction

Recombinant BirA Protein Feature

BirA Protein, E. coli, Recombinant (His & MBP Tag)

High Purity
> 95 % as determined by SDS-PAGE
Low Endotoxin
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