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UCHL3 Anticorpo, Anticorpo monoclonal de coelho, Antigen purificação por afinidade

  • UCHL3 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
  • UCHL3 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunoprecipitation
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Ratazana UCHL3 Informação sobre produtos de anticorpos
Imunogénio:Recombinant Rat UCHL3 protein (Catalog#80087-R07E)
Clone ID:
Tipo Ig:Rabbit IgG
Concentração:
Endotoxina:
Formulação:0.2 μm filtered solution in PBS
Preparação:Produced in rabbits immunized with purified, recombinant Rat UCHL3 (rR UCHL3; Catalog#80087-R07E; Q91Y78; Glu 2-Ala 230). UCHL3 specific IgG was purified by Rat UCHL3 affinity chromatography.
Ratazana UCHL3 Antibody WB Application Image
Ratazana UCHL3 Antibody IP Application Image
Other UCHL3 Antibody Products
UCHL3 Fundo

Ubiquitin carboxyl-terminal hydrolase isozyme L3, also known as UCH-L3, Ubiquitin thioesterase L3 and UCHL3, is a ubiquitin-protein hydrolase which belongs to the peptidase C12 family. It is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. UCHL3 is highly expressed in heart, skeletal muscle, and testis. UCHL1 and UCHL3 are two of the deubiquitinating enzymes expressed in the brain. These phenotypes indicate the importance of UCHL1 and UCHL3 in the regulation of the central nervous system. UCHL3 functions as a de-ubiquitinating enzyme where lack of its hydrolase activity may result in the prominent accumulation of ubiquitinated proteins and subsequent induction of stress responses in skeletal muscle. UCHL3 has also been identified as a tumor-specific antigen in colon cancer.

Ratazana UCHL3 Referências
  • Wood,M.A. et al., 2005, Hippocampus  15 (5):610-21.
  • Kwon,J. et al., 2006, Exp Anim  55 (1):35-43.
  • Setsuie,R. et al., 2009, Neurochem Int  54 (5-6):314-21.
  • Setsuie,R. et al., 2010, Neurochem Int  56 (8):911-8.
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    Catálogo: 80087-RP02-50
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