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UCHL3 Antibody, Rabbit MAb

Folha de dadosAnálisesProdutos relacionadosProtocolos
Rat UCHL3 Informação sobre produtos de anticorpos
Imunogénio:Recombinant Rat UCHL3 protein (Catalog#80087-R07E)
Clone ID:028
Tipo Ig:Rabbit IgG
Concentração:
Endotoxina:
Formulação:0.2 μm filtered solution in PBS with 5% trehalose
Preparação:This antibody was obtained from a rabbit immunized with purified, recombinant Rat UCHL3 (rR UCHL3; Catalog#80087-R07E; Q91Y78; Glu2-Ala230).
Rat UCHL3 Guia de utilização de anticorpos
Especificidade:Rat UCHL3
No cross-reactivity in ELISA with
Human UCHL3
Mouse UCHL3
Aplicação:ELISA

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Rat UCHL3. The detection limit for Rat UCHL3 is approximately 0.0195 ng/well.

Armazenamento:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other UCHL3 Antibody Products
UCHL3 Fundo

Ubiquitin carboxyl-terminal hydrolase isozyme L3, also known as UCH-L3, Ubiquitin thioesterase L3 and UCHL3, is a ubiquitin-protein hydrolase which belongs to the peptidase C12 family. It is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. UCHL3 is highly expressed in heart, skeletal muscle, and testis. UCHL1 and UCHL3 are two of the deubiquitinating enzymes expressed in the brain. These phenotypes indicate the importance of UCHL1 and UCHL3 in the regulation of the central nervous system. UCHL3 functions as a de-ubiquitinating enzyme where lack of its hydrolase activity may result in the prominent accumulation of ubiquitinated proteins and subsequent induction of stress responses in skeletal muscle. UCHL3 has also been identified as a tumor-specific antigen in colon cancer.

Rat UCHL3 Referências
  • Wood,M.A. et al., 2005, Hippocampus  15 (5):610-21.
  • Kwon,J. et al., 2006, Exp Anim  55 (1):35-43.
  • Setsuie,R. et al., 2009, Neurochem Int  54 (5-6):314-21.
  • Setsuie,R. et al., 2010, Neurochem Int  56 (8):911-8.
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    Catálogo: 80087-R028-50
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    DisponibilidadeIn Stock
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    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
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