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Sox2 Anticorpo, Anticorpo monoclonal de coelho, Antigen purificação por afinidade

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Human Sox2 Informação sobre produtos de anticorpos
Imunogénio:A synthetic peptide corresponding to the N-terminus of the Human Sox2.
Clone ID:
Tipo Ig:Rabbit IgG
Concentração:
Endotoxina:
Formulação:0.2 μm filtered solution in PBS with 5% trehalose
Preparação:Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human Sox2, and purified by antigen affinity chromatography.
Human Sox2 Guia de utilização de anticorpos
Especificidade:Human Sox2
Aplicação:WB, IHC-P, IP

WB: 1-10 μg/mL

IHC-P: 0.1-2 μg/mL

IP: 0.5-2 μg/mg of lysate

Armazenamento:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human Sox2 Antibody WB Application Image
Human Sox2 Antibody IHC Application Image
Sox2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Clicar para ampliar a imagem]
Caption:
Immunochemical staining of human Sox2 in human brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Sox2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
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Caption:
Immunochemical staining of human Sox2 in human glioma with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (polypeptide).
Human Sox2 Antibody IP Application Image
Other Sox2 Antibody Products
Sox2 Fundo

SOX2, also known as ANOP3, is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. SOX2 is critical for early embryogenesis and for embryonic stem cell pluripotency. It keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Defects in SOX2 can cause microphthalmia, syndromic, 3. A disease characterized by the rare association of malformations including uni- or bilateral anophthalmia or microphthalmia, and esophageal atresia with trachoesophageal fistula.

Human Sox2 Referências
  • Lu Y, et al., 2010, PLoS ONE. 5(6): e11022.
  • Gontan C, et al., 2008, Dev. Biol. 317 (1): 296-309.
  • Shi W, et al., 2006, J. Biol. Chem. 281 (33): 23319-25.
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