Encomenda rápida

REG1B Anticorpo, Anticorpo monoclonal de coelho

Folha de dadosAnálisesProdutos relacionadosProtocolos
Humano REG1B/PSPS2 Informação sobre produtos de anticorpos
Imunogénio:Recombinant Human REG1B protein (Catalog#11638-H08H)
Clone ID:029
Tipo Ig:Rabbit IgG
Concentração:
Formulação:0.2 μm filtered solution in PBS with 5% trehalose
Preparação:This antibody was obtained from a rabbit immunized with purified, recombinant Human REG1B (rh REG1B; Catalog#11638-H08H; NP_006498.1; Met 1-Asn 166).
Other REG1B/PSPS2 Antibody Products
REG1B Fundo

Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells, and could be associated with fibrocalculous pancreatopathy. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family consisting of four subtypes (types I, II, III, IV) and are involved in cancers and neurodegenerative diseases. Regenerating islet-derived 1 beta (REG1B), also known as Lithostathine-1-beta and Pancreatic stone protein 2 (PSPS2), is a types I Reg protein and contains one typical C-type lectin domain. REG1B is a 166-amino acid protein which has 22 amino acid substitutions in comparison with the previously isolated human REG1A, and it is was expressed only in pancreas. REG1B Is normally found in the exocrine pancreas, whereas in other tissues it appears either only under pathological conditions, such as Alzheimer's disease (brain), cancer (colon), or during regeneration such as neuronal sprouting in brain and pancreas regeneration. REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. The REG1A and REG1B gene and proteins could play different roles in the pancreas.

Humano REG1B Referências
  • Moriizumi S, et al. (1994) Isolation, structural determination and expression of a novel reg gene, human regI beta. Biochim Biophys Acta. 1217(2): 199-202.
  • Sanchez D, et al. (2001) Preferential expression of reg I beta gene in human adult pancreas. Biochem Biophys Res Commun. 284(3): 729-37.
  • Boonyasrisawat W, et al. (2002) Analysis of the reg1alpha and reg1beta gene transcripts in patients with fibrocalculous pancreatopathy. Southeast Asian J Trop Med Public Health. 33(2): 365-72.
  • Product nameProduct name
    Size / Price
    Catálogo: 11638-R029-50
    Preço de catálogo: 
    Preço:      (You Save: )
    Tamanho:
    50 µg
    100 µg
    Quantidade:+-
    DisponibilidadeIn Stock
    Acrescentar a carrinhoBulk Discount Requiry
    Contact Us
    Imagens
        Itens recentemente visualizados
          All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
          Tenha em atenção o seguinte: Todos os produtos destinam-se "A FINS EXCLUSIVOS DE INVESTIGAÇÃO E NÃO DEVEM SER UTILIZADOS PARA EFEITOS DE DIAGNÓSTICO OU TERAPÊUTICOS"