Carboxypeptidase A2 cDNA ORF Clone, Human, N-HA tag General Information
Full length Clone DNA of Human carboxypeptidase A2 (pancreatic) with N terminal HA tag.
Enhanced CMV promoter
HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Antibiotic in Mammalian cell
Stable or Transient mammalian expression
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
Carboxypeptidase A2 cDNA ORF Clone, Human, N-HA tag Alternative Names
CPA2 cDNA ORF Clone, Human
Carboxypeptidase A2 Background Information
Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. Three different forms of human pancreatic procarboxypeptidase A have been isolated, and the A1 and A2 forms are always secreted as monomeric proteins with different biochemical properties.
Catasus, L. et al., 1995. J. Biol. Chem. 270: 6651-6657. Aloy, P. et al., 1998, Biol. Chem. 379: 149-155. Laethem, RM. et al., 1996, Arch. Biochem. Biophys.332: 8-18.