CCL14 cDNA ORF Clone, Human, C-HA tag General Information
Full length Clone DNA of Human chemokine (C-C motif) ligand 14 with C terminal HA tag.
Enhanced CMV promoter
HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Antibiotic in Mammalian cell
Stable or Transient mammalian expression
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
CCL14 cDNA ORF Clone, Human, C-HA tag Alternative Names
CC-1 cDNA ORF Clone, Human;CC-3 cDNA ORF Clone, Human;CKB1 cDNA ORF Clone, Human;FLJ16015 cDNA ORF Clone, Human;HCC-1 cDNA ORF Clone, Human;HCC-1(1-74) cDNA ORF Clone, Human;HCC-1/HCC-3 cDNA ORF Clone, Human;HCC-3 cDNA ORF Clone, Human;MCIF cDNA ORF Clone, Human;NCC-2 cDNA ORF Clone, Human;NCC2 cDNA ORF Clone, Human;SCYA14 cDNA ORF Clone, Human;SCYL2 cDNA ORF Clone, Human;SY14 cDNA ORF Clone, Human
CCL14 Background Information
CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is of recent interest because of its natural ability, upon proteolytic processing of the first eight NH2-terminal residues, to bind to and signal through the human immunodeficiency virus type-1 (HIV-1) co-receptor, CC chemokine receptor 5 (CCR5). Embryo implantation is a complex process involving blastocyst attachment to the endometrial epithelium and subsequent trophoblast invasion of the decidua. We have previously shown that the chemokines CX3CL1 and CCL14 are abundant in endometrial vasculature, epithelial, and decidual cells at this time, and that their receptors, CX3CR1 and CCR1, are present on invading human trophoblasts. CX3CL1 and CCL14 promote trophoblast migration.
chemokine (C-C motif) ligand 14
Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.Knappe S, et al. (1996) HCC-1, a novel chemokine from human plasma. J Exp Med. 183: 295-9.Naruse, et al. (1996) A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2. Genomics. 34: 236-40.
CCL14/HCC-1/HCC-3 related areas, pathways, and other information