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FCRL1 / FCRH1 Anticorpo, Anticorpo monoclonal de coelho, Antigen purificação por afinidade

    Folha de dadosAnálisesProdutos relacionadosProtocolos
    Humano FCRL1 Informação sobre produtos de anticorpos
    Imunogénio:Recombinant Human FCRL1 / FCRH1 protein (Catalog#11536-H08H)
    Clone ID:
    Tipo Ig:Rabbit IgG
    Concentração:
    Formulação:0.2 μm filtered solution in PBS with 5% trehalose
    Preparação:Produced in rabbits immunized with purified, recombinant Human FCRL1 / FCRH1 (rh FCRL1 / FCRH1; Catalog#11536-H08H; NP_001890.1; Met 1-Asn 303). FCRL1 / FCRH1 specific IgG was purified by Human FCRL1 / FCRH1 affinity chromatography.
    Other FCRL1 Antibody Products
    FCRL1/FCRH1 Fundo

    Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I  membrane protein which contains three Ig-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.

    Humano FCRL1/FCRH1 Referências
  • Du X. et al., 2008, Blood. 111 (1): 338-43.
  • Kazemi T. et al., 2008, Int J Cancer. 123 (9): 2113-9.
  • Baranov K. et al., 2008, J Immunol Methods. 332 (1-2): 73-81.
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